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TOYP Singapore 2015

A/P Jonathan Loh Yuin-Han

Merit Award · Science & Technology

Year

2015

Award

Merit Award

Occupation

Deputy Executive Director (Research), A*STAR

Organisation

Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR)

Biography

Dr Jonathan Loh Yuin-Han is the Deputy Executive Director (Research) at the Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), where he also serves as the Director of Cellular & Molecular Therapy (CMT) Division. Concurrently, he is a Professor (Adjunct) at the NUS Yong Loo Lin School of Medicine Department of Physiology, NUS Faculty of Science Department of Biological Sciences, and a Faculty member of the NUS Graduate School of Integrative Sciences and Engineering.

He received his BSc 1st Class Honours in Biology from the National University of Singapore and completed his PhD research as an A*STAR Scholar at the Stem Cell and Developmental Biology group, Genome Institute of Singapore under Prof Ng Huck Hui. During his postdoctoral fellowship at the Division of Pediatric Hematology and Oncology, Boston Children's Hospital, Harvard Medical School under Dr George Daley, he pioneered the use of human blood cells for reprogramming to induced pluripotent stem cells (iPSCs) and the modelling of congenital and somatic hematologic diseases using iPSCs.

Dr Loh received the Ten Outstanding Young Person (TOYP) Award in 2015 for Scientific and Technological Development from Junior Chamber International (JCI) Singapore, recognizing his contributions to stem cell research. He serves as president of the Stem Cell Society Singapore (SCSS), on the International Committee at the International Society for Stem Cell Research (ISSCR), and on the Executive Council for the Singapore Association for the Advancement of Science (SAAS). He has co-founded two biotech start-ups, InnoCellular Tech and Genovn Therapeutics, and serves on the Board of Directors for Nasdaq-listed Cytomed Therapeutics.

Achievements

  • Pioneered the use of human blood cells for reprogramming to induced pluripotent stem cells (iPSCs).
  • Conducted first detailed study on proviral silencing in embryonic stem cells, advancing understanding of stem cell biology.
  • Co-founded two biotech start-ups, InnoCellular Tech and Genovn Therapeutics.
  • Developed the first single-cell atlas of human and porcine eyes, mapping genes involved in eye disorders.
  • Serves as Board of Directors for Nasdaq-listed Cytomed Therapeutics and president of Stem Cell Society Singapore.

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